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Index > Protein center > Tap2(Gene name) > Mouse
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  • Tap2 (Gene name),
  • Antigen peptide transporter 2 (Protein name ),  TAP2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Tap2(Abcb3;Ham-2;Ham2);
    Protein name:
    Antigen peptide transporter 2(APT2);
    Alternative:
    Histocompatibility antigen modifier 2;ATP-binding cassette sub-family B member 3;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Heterodimer of TAP1 and TAP2.
    Function:
    Involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. Also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin.
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein The transmembrane segments seem to form a pore in the membrane.
    Protein Attributes:
    Sequence length:
    702
    Sequence:
    50:
    MALSYLRPWV | SLLLADMALL | GLLQGSLGNL | LPQGLPGLWI | EGTLRLGVLW | 
    100:
    GLLKVGELLG | LVGTLLPLLC | LATPLFFSLR | ALVGGTASTS | VVRVASASWG | 
    150:
    WLLAGYGAVA | LSWAVWAVLS | PAGVQEKEPG | QENRTLMKRL | LKLSRPDLPF | 
    200:
    LIAAFFFLVV | AVWGETLIPR | YSGRVIDILG | GDFDPDAFAS | AIFFMCLFSV | 
    250:
    GSSFSAGCRG | GSFLFTMSRI | NLRIREQLFS | SLLRQDLGFF | QETKTGELNS | 
    300:
    RLSSDTSLMS | RWLPFNANIL | LRSLVKVVGL | YFFMLQVSPR | LTFLSLLDLP | 
    350:
    LTIAAEKVYN | PRHQAVLKEI | QDAVAKAGQV | VREAVGGLQT | VRSFGAEEQE | 
    400:
    VSHYKEALER | CRQLWWRRDL | EKDVYLVIRR | VMALGMQVLI | LNCGVQQILA | 
    450:
    GEVTRGGLLS | FLLYQEEVGQ | YVRNLVYMYG | DMLSNVGAAE | KVFSYLDRKP | 
    500:
    NLPQPGILAP | PWLEGRVEFQ | DVSFSYPRRP | EKPVLQGLTF | TLHPGTVTAL | 
    550:
    VGPNGSGKST | VAALLQNLYQ | PTGGQLLLDG | EPLTEYDHHY | LHRQVVLVGQ | 
    600:
    EPVLFSGSVK | DNIAYGLRDC | EDAQVMAAAQ | AACADDFIGE | MTNGINTEIG | 
    650:
    EKGGQLAVGQ | KQRLAIARAL | VRNPRVLILD | EATSALDAQC | EQALQNWRSQ | 
    700:
    GDRTMLVIAH | RLHTVQNADQ | VLVLKQGRLV | EHDQLRDGQD | VYAHLVQQRL | 
    702:
    EA
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    Pfam:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse APT2
    Cat.:
    E10018h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse APT2
    Cat.:
    E10018m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse APT2
    Cat.:
    E10018r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Mouse APT2
    Cat.:
    U10018h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse APT2
    Cat.:
    U10018m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse APT2
    Cat.:
    U10018r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse APT2
    Cat.:
    P10018Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse APT2
    Cat.:
    P10018Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse APT2
    Cat.:
    P10018Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse APT2
    Monoclonal Antibody for Mouse APT2
    Monoclonal Antibody for Mouse APT2
    Protein for Mouse APT2
    Protein for Mouse APT2
    Protein for Mouse APT2

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    Linearity
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    References
    1. 1.
      "Major histocompatibility complex (MHC)-encoded HAM2 is necessary for antigenic peptide loading onto class I MHC molecules."
      Yang Y. , Frueh K. , Chambers J. , Waters J.B. , Wu L. , Spies T. , Peterson P.A.
      J. Biol. Chem.267:11669-11672(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
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